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Pristinamycin CAS: 270076-60-3
Pristinamycin ni umuti uhuriweho w’imiti irwanya udukoko ugizwe n’ibice bibiri bikora, pristinamycin I na pristinamycin II. Uri mu itsinda rya streptogramin rya antibiyotike kandi ugira ingaruka ku mikorobe no kwica bagiteri zitandukanye, harimo Staphylococcus aureus na Streptococcus pneumoniae. Pristinamycin ikora mu kubuza poroteyine ya bagiteri gukora, bigatuma igira ingaruka nziza mu kuvura indwara z’uruhu n’imitsi yoroshye, indwara z’ubuhumekero, n’izindi ndwara za bagiteri ziterwa n’udukoko twibasirwa n’udukoko.
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Ribostamisini sulfate CAS: 53797-35-6
Ribostamycin sulfate ni umuti urwanya aminoglycoside ukomoka kuri Streptomyces griseoluteus. Ugaragaza imbaraga zikomeye zo kwica bagiteri mu miterere itandukanye ya bagiteri za garama-negative na zimwe muri garama-positive mu kubuza poroteyine gukora. Ribostamycin sulfate ikoreshwa cyane mu kuvura indwara zitandukanye, harimo indwara zo mu nzira y'inkari, indwara zo mu nzira y'ubuhumekero, indwara zo mu ruhu n'ingingo zoroshye, ndetse n'indwara ziterwa na bagiteri zishobora kwibasirwa n'imiti.
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Rifampicin CAS: 13292-46-1
Rifampicin, izwi kandi nka rifampin, ni umuti urwanya indwara nyinshi ukomoka mu itsinda rya rifamycin. Ukoreshwa cyane mu kuvura igituntu, ibibembe, n'izindi ndwara zandurira mu mikorobe. Rifampicin ikora mu kubuza imikorere ya RNA muri bagiteri, bityo ikabangamira ubushobozi bwazo bwo kororoka no kubaho. Bitewe n'imikorere yayo ikomeye yo kurwanya indwara za mikorobe n'ubushobozi bwayo mu kurwanya ubwoko bwa mycobacterial, rifampicin ni igice cy'ingenzi cy'imiti ivanze yo kuvura igituntu n'izindi ndwara zandura.
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Puromycin dihydrochloride CAS: 58-58-2
Puromycin dihydrochloride ni umuti ukomeye wo gukumira antibiyotike na poroteyine ukomoka kuri Streptomyces alboniger. Ikunze gukoreshwa mu bushakashatsi bwa biology ya molekile kugira ngo ibuze uburyo bwo gukora poroteyine mu turemangingo binyuze mu guhagarika ihinduka ry’ingirabuzimafatizo mu gihe cyo gukora poroteyine. Puromycin dihydrochloride yinjizwa mu miyoboro mishya ya peptide, bigatuma polypeptides zidatunganyije zirekurwa ndetse amaherezo n’urupfu rw’uturemangingo. Bitewe n’imikorere yayo yihariye, puromycin dihydrochloride ni igikoresho cy’agaciro mu kwiga gukora poroteyine, imikorere ya ribosome, imikorere ya gene, n’ubushobozi bw’uturemangingo mu igerageza.
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Protionamide CAS: 14222-60-7
Protionamide ni umuti urwanya indwara zo mu bwoko bwa thioamide, ukoreshwa cyane cyane mu kuvura igituntu kidakira imiti myinshi. Ukora mu kubuza ikorwa rya aside mycolic mu rukuta rw'uturemangingo twa bagiteri, bigatera isenyuka rya Mycobacterium tuberculosis. Protionamide ikunze gutangwa hamwe n'indi miti irwanya igituntu nk'igice cy'uburyo burambuye bwo kuvura igituntu kidakira imiti.
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Potasiyumu clavulanate CAS: 61177-45-5
Potasiyumu clavulanate ni umuti ubuza β-lactamase ukunze guhuzwa na antibiyotike zimwe na zimwe kugira ngo wongere ubushobozi bwazo mu kurwanya indwara za bagiteri. Ikora mu gukumira kwangirika kwa antibiyotike n'imisemburo ya bagiteri, bityo ikarushaho gukora neza no kunoza umusaruro w'ubuvuzi. Potasiyumu clavulanate ikoreshwa cyane mu bicuruzwa bivanze na antibiyotike nka amoxicillin mu kuvura indwara zitandukanye za bagiteri.
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Retapamulin CAS: 224452-66-8
Retakamulin ni umuti ukoreshwa mu kuvura indwara z’uruhu za bagiteri, cyane cyane impetigo iterwa n’ubwoko bwa Staphylococcus aureus na Streptococcus pyogenes zishobora kwibasirwa n’indwara. Retakamulin ikora mu kubuza poroteyine za bagiteri gukora, bigatuma bagiteri zandura zicika burundu kandi indwara z’uruhu zigashira burundu.
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Staurosporine, streptomyces staurosporeus CAS:62996-74-1
Staurosporine ni ikintu karemano cyakuwe muri bagiteri ya Streptomyces staurosporeus. Ishyirwa mu cyiciro cya alkaloid ikomeye ifite imikorere ikomeye ya biyoloji, cyane cyane mu gukumira poroteyine kinase no gutera apoptosis y'uturemangingo. Staurosporine yasuzumwe cyane kubera imiterere yayo mu by'imiti, harimo n'ubushobozi bwayo bwo kurwanya kanseri ndetse n'uruhare rwayo nk'igikoresho cy'ubushakashatsi mu bushakashatsi ku turemangingo.
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Umunyu wa Phosphomycin disodium CAS:26016-99-9
Umunyu wa Phosphomycin disodium ni umuti urwanya indwara nyinshi ukoreshwa mu kuvura indwara zitandukanye za bagiteri. Uri mu bwoko bwa aside phosphonic kandi ugabanya imikorere y’uturemangingo twa bagiteri. Iyi fu y’umweru irashongesha cyane mu mazi kandi ikunze gutangwa mu mitsi cyangwa mu kanwa. Umunyu wa Phosphomycin disodium uzwiho kugira akamaro mu kurwanya bagiteri nyinshi za garama-positive na garama-negative, bigatuma uba amahitamo menshi yo kuvura indwara.
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Phleomycin CAS: 11006-33-0
Phleomycin ni antibiyotike ikomeye ikoreshwa mu bushakashatsi bwa biology ya molekile mu guhitamo uturemangingo turimo gene ishimishije. Ifite uburyo bwo gukora busaba gucikamo ADN, Phleomycin igira ingaruka nziza ku bwoko butandukanye bwa bagiteri kandi yakoreshejwe cyane mu bushakashatsi butandukanye. Iyi antibiyotike ikunze gukoreshwa hamwe n'ibindi bimenyetso byo guhitamo kugira ngo habeho imirongo ihamye y'uturemangingo hamwe n'impinduka zifuzwa mu ngirabuzimafatizo. Phleomycin iboneka mu bwoko bw'amazi n'ifu, bigatuma ikoreshwa mu buryo butandukanye kandi ikaba yoroshye gukoreshwa mu bushakashatsi butandukanye. Abashakashatsi bishimira imikorere yayo myiza n'uburyo yizewe mu guhitamo uturemangingo twahinduwe, bigatuma iba igikoresho cy'agaciro mu bushakashatsi bw'ubuhanga mu ngirabuzimafatizo.
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Umunyu wa potassium wa Penicilline V CAS: 132-98-9
Umunyu wa potassium wa Penicillin V ni umuti uvura indwara zandura za bagiteri. Urimo penicillin V, umunyu wa potassium wo mu bwoko bwa phenoxymethylpenicillin. Penicillin V ikora mu kubangamira ikorwa rya peptidoglycan mu rukuta rw'uturemangingo twa bagiteri. Ibi bigabanya intege nke z'urukuta rw'uturemangingo kandi bikica cyangwa bikabuza gukura kwa bagiteri zishobora kwandura. Uboneka nk'ibinini cyangwa imiti ikoreshwa mu kuvura indwara zoroheje kugeza ku ziciriritse mu bitaro.
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Umunyu wa Penicilline G (umunyu wa Benzylpenicilline) CAS: 69-57-8
Umunyu wa sodium wa Penicillin G ni umuti urwanya indwara ugizwe na penisiline G mu buryo bwa sodium. Ukora mu kubuza ikorwa rya peptidoglycan mu nkuta z'uturemangingo twa bagiteri, ukica bagiteri zishobora kwandura. Umunyu wa sodium wa Penicillin G uboneka nk'udukoko tw'umweru cyangwa hafi ya umweru cyangwa ifu igomba kongera gushyirwamo umuti mbere yo guterwa inshinge. Utanga uburyo bwo gutanga penisiline G mu kuvura indwara za bagiteri.
