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Tetracycline CAS: 60-54-8
Tetracycline ni antibiyotike ifite imiterere myinshi iri mu bwoko bwa tetracycline, ikomoka ku kintu karemano cya chlortetracycline. Ibuza poroteyine ya bagiteri gukorana na ribosome ya bagiteri, bityo ikabuza aminoacyl-tRNA gufatana na mRNA-ribosome complex. Ubu buryo bw'imikorere butuma habaho ingaruka za bagiteri ku bwoko butandukanye bwa bagiteri za gram-positive na gram-negative, ndetse na protozoa zimwe na zimwe.
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Teicoplanin CAS: 61036-62-2
Teicoplanin ni umuti wa glycopeptide ukomoka kuri Actinoplanes teichomyceticus, ugira ingaruka nziza ku bagiteri zitandukanye za gram-positive harimo na Staphylococcus aureus (MRSA) irwanya methicillin. Ibuza imikorere y'urukuta rw'uturemangingo twa bagiteri binyuze mu gufatana n'igice cya D-alanyl-D-alanine cy'ibintu bya mbere bya peptidoglycan, bigatuma uturemangingo twica kandi tugakora bagiteri. Teicoplanin ikunze gukoreshwa mu buvuzi mu kuvura indwara zikomeye ziterwa n'uturemangingo twa gram-positive.
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Sulfisoxazole (4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide) CAS:127-69-5
Sulfisoxazole, izwi kandi nka sulfafurazole, ni antibiyotike ya sulfonamide iri mu bwoko bwa sulfa. Sulfisoxazole, yiswe 4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide, ibuza bagiteri gukura mu buryo bubangamira ikorwa rya aside folike. Ubu buryo bwo gukora bugamije dihydropteroate synthase, enzyme ikenewe mu gukora folate ya bagiteri, bityo ikabangamira iterambere ryayo no kwiyongera kwayo.
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Sulfapiridine CAS: 144-83-2
Sulfapyridine ni umuti urwanya bagiteri wa sulfonamide wakoreshwaga mu kuvura indwara zandura, cyane cyane mu Ntambara ya Kabiri y'Isi Yose. Uri mu bwoko bw'imiti ya sulfa, ibuza bagiteri gukura binyuze mu kubangamira ikorwa rya aside folike. Sulfapyridine igira ingaruka za bagiteri mu kwibasira dihydropteroate synthase, enzyme ikenewe cyane mu gukora folate muri bagiteri.
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Tazobactam CAS: 89786-04-9
Tazobactam ni umuti ubuza beta-lactamase kongera imikorere ya antibiyotike za beta-lactam mu kuzirinda kwangirika kwa enzymes za beta-lactamase zikorwa na bagiteri nyinshi zirwanya indwara. Ikunze gukoreshwa hamwe na antibiyotike za beta-lactam nka piperacillin kugira ngo yongere imikorere yazo mu kurwanya indwara zitandukanye za bagiteri. Tazobactam igarura neza imikorere ya antibiyotike za beta-lactam mu kurwanya bagiteri zikora beta-lactamase, cyane cyane ibinyabuzima bidafite gram.
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Tigecycline CAS: 220620-09-7
Tigecycline ni antibiyotike ya glycylcycline ifite imiterere myinshi ibuza poroteyine za bagiteri kwihambira ku gice cya 30S ribosomal, bityo ikagira ingaruka za bagiteri ku bwoko butandukanye bwa bagiteri za gram-positive na gram-negative, harimo na za virusi zirwanya imiti myinshi. Ifitanye isano n'imiterere ya tetracycline ariko ifite imbaraga zo kurwanya ubwoko burwanya bitewe n'imikorere yayo yihariye n'impinduka mu miterere.
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Umunyu wa sodium wa Sulbactam CAS: 69388-84-7
Umunyu wa sodium wa Sulbactam ni umuti ubuza beta-lactamase ukoreshwa cyane hamwe na antibiyotike zimwe na zimwe mu kurwanya indwara za bagiteri. Ukora mu kubuza imikorere ya enzymes za beta-lactamase zikorwa na bagiteri, zishobora gutuma antibiyotike zidakora neza. Mu gukumira kwangirika kwa antibiyotike nka penicilline na cephalosporins, umunyu wa sodium wa sulbactam ufasha kongera ubushobozi bwazo bwo kurwanya antibiyotike. Iki kintu gikunze gukoreshwa hamwe na antibiyotike nka ampicillin kugira ngo kigire ingaruka nziza ku bwoko butandukanye bwa bagiteri zishobora kwibasirwa.
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Sulfadimidine CAS: 57-68-1
Sulfadimidine, izwi kandi nka sulfamethazine, ni umuti urwanya udukoko wa sulfonamide ukoreshwa mu kuvura indwara zandura. Uri mu bwoko bw'imiti irwanya udukoko izwi nka sulfa, ikora mu kubuza gukura no kororoka kwa bagiteri. Sulfadimidine ibangamira ikorwa rya aside folike muri bagiteri, igice cy'ingenzi mu kubaho kwazo, bigatuma zibaho, bigatuma bagiteri nyinshi zirwanya bagiteri za garama-positive na garama-negative.
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Umunyu wa sodium wa Sulfacetamide CAS: 6209-17-2
Umunyu wa Sulfacetamide sodium ni umuti uva muri sulfacetamide, umuti urwanya udukoko twa sulfonamide ukunze gukoreshwa mu miti ivura indwara z’uruhu n’amaso. Iyi miterere y’umunyu yongera ubushobozi bwo gushonga no kudahungabana kwa sulfacetamide, bigatuma ikoreshwa mu miti itandukanye. Umunyu wa Sulfacetamide sodium utuma bagiteri zikura, cyane cyane izitera indwara nka acne vulgaris, seborrheic dermatitis, n’indwara z’amaso nka conjunctivitis. Ubangamira imikorere ya bagiteri ya folate, ukibasira ubwoko bwinshi bwa bagiteri za garama-positive na garama-negative.
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Streptomycin sulfate CAS: 3810-74-0
Streptomycin sulfate ni umuti urwanya udukoko uri mu itsinda rya aminoglycoside. Ukomoka kuri bagiteri ya Streptomyces griseus kandi ukoreshwa cyane mu kuvura indwara za bagiteri. Streptomycin sulfate ikora mu kubuza poroteyine ya bagiteri gukora, bityo ikica neza bagiteri zishobora kwibasirwa. Akenshi ikoreshwa mu kuvura igituntu, indwara ya plaque, tularemia, n'izindi ndwara zimwe na zimwe ziterwa na bagiteri zishobora kwibasirwa. Streptomycin sulfate ikunze kuboneka mu buryo bw'urushinge kandi itangwa haba mu mitsi cyangwa mu mitsi ikurikiranwa na muganga.
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Umunyu wa sodium wa Sulfamethoxazole CAS: 4563-84-2
Umunyu wa sodium wa Sulfamethoxazole ni umuti uva muri sulfamethoxazole, umuti wica udukoko wa sulfonamide ukoreshwa mu kuvura indwara zandura. Iyi miterere y'umunyu yongera ubushobozi bwo gushonga no kudahungabana kwa sulfamethoxazole, bigatuma ikoreshwa mu miti itandukanye. Umunyu wa sodium wa Sulfamethoxazole ugira ingaruka mbi ku mikorere ya bagiteri mu kubuza ikorwa rya aside folike muri bagiteri, ikaba ari ingenzi mu gukura no kwiyongera kwazo. Igira ingaruka nziza ku bwoko butandukanye bwa bagiteri zifite garama imwe na garama imwe.
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Sulfametoksazole CAS: 723-46-6
Sulfamethoxazole ni antibiyotike ya sulfonamide ikunze gukoreshwa hamwe na trimethoprim kugira ngo hakorwe umuti ukomeye wa antibiyotike uzwi nka co-trimoxazole cyangwa trimethoprim-sulfamethoxazole (TMP-SMX). Iri mu bwoko bw'imiti irwanya udukoko izwi nka sulfa, ibuza gukura kwa bagiteri mu kubangamira ikorwa rya aside folike. Sulfamethoxazole yibasira by'umwihariko dihydropteroate synthase, enzyme igira uruhare mu ikorwa rya folate, bityo ikagira ingaruka mbi ku bwoko bwinshi bwa bagiteri za garama-positive na garama-negative.
