2 ′ - (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium yumunyu ni imiti yimiti ikoreshwa muburyo bwo gusuzuma no gukora ubushakashatsi.Ni fluorescente yanditseho inkomoko ya acide sialic, ubwoko bwa molekile ya karubone ya hydrata iboneka hejuru ya selile.
Uru ruganda rukoreshwa nka substrate ya enzymes yitwa neuraminidase, ikora kugirango ikureho ibisigazwa bya acide sialic muri glycoproteine na glycolipide.Iyo iyi misemburo ikora kuri 2 ′ - (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium umunyu, irekura ibicuruzwa bya fluorescent bizwi nka 4-methylumbelliferone.
Florescence ikorwa nuruvange irashobora gupimwa no kugereranywa, igatanga amakuru kubikorwa bya enzymes ya neuraminidase.Ibi ni ingirakamaro cyane cyane mukwiga indwara zitandukanye nuburyo bujyanye na aberrant sialic aside metabolism.
Uru ruganda rukoreshwa kandi muburyo bwo gusuzuma, nko mugushakisha kwandura virusi zirimo ibikorwa bya neuraminidase.Muri ubu bushakashatsi, urugimbu rukoreshwa mu kwerekana ko hari virusi yihariye cyangwa gusuzuma imikorere ya neuraminidase inhibitor mu kuvura virusi.