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1 '1-Bis (diphenylphosphino)ferrocene Palladium(Ⅱ)chloride dichloromethane chloride CAS:95464-05-4
1,1-Bis (diphenylphosphino)ferrocene Palladium (II) Chloride Dichloromethane Complex, ifite formula ya chimique [Pd (dppf)Cl₂·CH₂Cl₂], ni igikoresho cya organometallic kirimo palladium (II) ihujwe na dppf ligand na chloride mu cyumyunyungugu cya dichloromethane. Ikunze gukoreshwa mu guhuza organic na catalysis.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
N-(6-Bromopyridin-2-yl)thiourea ni ikinyabutabire kirangwa no kuba hari itsinda ry’imikorere ya thiourea rifatanye n’igice cya 6-bromopyridin-2-yl. Iki kinyabutabire cyakunzwe cyane mu buvuzi bitewe n’ibikorwa byacyo bitandukanye by’imiti n’uburyo gishobora gukoreshwa mu kuvura. Imiterere yacyo yihariye itanga uburyo bwo gushushanya imiti mishya ifite intego zihariye za biyoloji, bigatuma iba ingirakamaro mu kuvumbura no guteza imbere imiti.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS:269409-97-4
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, izwi cyane nka TMDBP, ni igikoresho cy’ibinyabutabire kiri mu itsinda rya esters za phenolic boronic. Imiterere ya molekile yayo igizwe n’itsinda rya phenolic hydroxyl rifatanye n’impeta ya phenyl ifite moiety ya ester ya cyclic irimo boron. Iki kintu gifite akamaro mu guhuza organic, cyane cyane muri Suzuki-Miyaura cross-coupling reactions, aho gikora nk'ikintu cy'agaciro cya ester ya boronic. Byongeye kandi, imiterere yayo ya boronate ihamye hamwe n’imiterere yayo idakora neza bituma igira akamaro mu gushushanya ligands zo guhindura ibyuma no mu iterambere ry’ibikoresho bikora.
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1-Methyl-4-pyrazole aside boronic ester pinacol CAS: 761446-44-0
1-Methyl-4-pyrazole boronic acid pinacol ester ni igikoresho cy’ibinyabutabire gishyirwa mu cyiciro cya ester boronic. Imiterere ya molekile yayo igizwe n’igice cya aside boronic gifatanye n’impeta ya pyrazole yasimbuwe n’itsinda rya ester ya pinacol (-OC (CH₃)₂C (CH₃)₂O-). Iki gikora gifite akamaro kanini mu guhuza ibinyabuzima, cyane cyane mu mikorere ya Suzuki-Miyaura, aho gikora nk’igikoresho cy’ubuhanga mu guhindura ester ya boronic. Byongeye kandi, guhagarara kwayo, gukora neza, no guhuza n’imiterere itandukanye y’imikorere bituma igira akamaro mu gukora imiti, imiti ikoreshwa mu buhinzi, n’ibikoresho bikora.
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![Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG285.png)
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6
Cyclopenta [b]pyrrole-3a (1H)-methanol, hexahydro- ni imvange y’ibice bibiri ivanze ifite imiterere y’ibanze ya cyclopenta [b]pyrrole n’uruhererekane rw’uruhande rwa hexahydro-1H-pyrrole-3a (1H)-methanol. Iyi molekile ni ingenzi mu buvuzi bitewe n’ibikorwa byayo bishobora gukorwa mu buvuzi. Imiterere yayo yihariye itanga amahirwe yo guteza imbere imiti mishya, cyane cyane yibasira indwara z’imitsi n’izindi ndwara aho guhindura uburyo bwo kwakira no gutwara ibintu mu buryo bwa neurotransmitter ari ingenzi cyane. Cyclopenta [b]pyrrole-3a (1H)-methanol, hexahydro- ikora nk'urubuga rw’abahanga mu buvuzi ba shimi bashakisha imiti mishya ifite imiterere myiza ya pharmacokinetic kandi igagabanya ingaruka mbi.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
Aside ya Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic ni molekyuli ikomeye irimo impeta ya pyrrolidine yasimbuwe n'itsinda rya tert-butoxycarbonyl ku mwanya wa 1 n'itsinda rya 3-(trifluoromethyl)phenyl ku mwanya wa 4. Iki kinyabutabire gifite akamaro mu buvuzi, ahanini bitewe n'ubushobozi bwacyo nk'ikinyabutabire mu miterere y'imiti. Imiterere yacyo igoye itanga amahirwe yo gukora imiti mishya ifite imiterere yihariye mu buvuzi, cyane cyane mu nzira ziterwa n'indwara ziterwa n'ububyimbirwe, kanseri, cyangwa indwara z'imitsi yo mu mutwe.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1262849-90-0
(3R, 4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ni ikinyabutabire kirangwa n'impeta ya pyrrolidine yasimbuwe n'itsinda rya ethyl ku mwanya wa 3 n'itsinda rya tert-butyl ku mwanya wa 1. Iki kinyabutabire cyakuruye ibitekerezo mu buvuzi bitewe n'imiterere yacyo ya stereochemical n'ikoreshwa rya farumasi. Imiterere yacyo yihariye itanga inzira zo gushushanya imiti mishya ifite intego zihariye za biyoloji, bigatuma iba umutungo w'agaciro mu kuvumbura no guteza imbere imiti.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1233501-65-9
Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ni ikinyabutabire kigizwe n'impeta ya pyrrolidine yasimbuwe n'itsinda rya ethyl ku mwanya wa 3 n'itsinda rya tert-butyl ku mwanya wa 1. Iki kinyabutabire cyakunzwe cyane mu buvuzi bitewe n'imiterere yacyo n'ikoreshwa ryacyo mu buvuzi. Imiterere yacyo yihariye itanga amahirwe yo gushushanya imiti mishya ifite intego zihariye za biyoloji, bigatuma iba ingirakamaro mu kuvumbura no guteza imbere imiti.
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4-Hydroxyphenylboronic aside pinacol ester CAS:269409-70-3
4-Hydroxyphenylboronic acid pinacol ester, izwi kandi nka 4-HPBA pinacol ester, ni igikoresho cy’ibinyabutabire kiri mu cyiciro cya esters boronic. Imiterere ya molekile yayo igizwe n’igice cya aside boronic gifatanye n’impeta ya phenyl yasimbuwe n’itsinda rya esters pinacol (-OC (CH₃)₂C (CH₃)₂O-). Iki kintu gifite akamaro kanini mu guhuza ibinyabuzima, cyane cyane mu mikorere ya Suzuki-Miyaura, aho gikora nk'igikoresho cy’ubuhanga mu guhindura esters boronic. Byongeye kandi, guhagarara kwayo, koroshya kuyikoresha, no guhuza n’imiterere itandukanye y’imikorere bituma igira akamaro mu guhuza imiti, ibintu karemano, n’ibikoresho bikora.
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![Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU259.png)
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride ni ikinyabutabire kigizwe n'itsinda ry'imikorere ya carbamate rifatanye n'impeta ya piperidine ryasimbuwe n'itsinda rya benzyl kuri atome ya azote n'itsinda rya propyl kuri atome ya karuboni. Iki kinyabutabire cyateje ubushake mu buvuzi bitewe n'imiterere yacyo n'uburyo gishobora gukoreshwa mu buvuzi. Imiterere yacyo yihariye itanga amahirwe yo gushushanya imiti mishya ifite intego zihariye za biyoloji, bigatuma iba umutungo w'agaciro mu kuvumbura no guteza imbere imiti.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic aside CAS: 333432-28-3
9,9-Dimethyl-9H-fluoren-2-yl-boronic aside, ikunze kwitwa DMFBA, ni igikoresho cy’ibinyabutabire kiri mu itsinda rya aside boronic. Imiterere ya molekile yayo ifite aside boronic ifatanye n’urukuta rwa fluorene rwasimbuwe n’amatsinda abiri ya methyl kuri 9-position. Iki kintu gifite akamaro kanini mu guhuza ibinyabuzima, cyane cyane mu mikorere ya Suzuki-Miyaura, aho gikora nk'igikoresho cy’aside boronic gifite ubushobozi bwinshi bwo kugihindura. Byongeye kandi, imiterere yacyo ikomeye kandi idakomeye ituma kigira akamaro mu gushushanya ligand mu mikorere y’ibyuma bihinduka ndetse no mu iterambere ry’ibikoresho bikora.
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4-aside karboksifeniliboronike CAS: 14047-29-1
4-Aside Carboxyphenylboronic, izwi kandi nka 4-Carboxyphenylboronic aside cyangwa 4-CPBA, ni igikoresho cy’ibinyabutabire kiri mu itsinda rya aside boronic. Irangwa n’itsinda ryayo rikora aside boronic (-B(OH)₂) rifatanye n’impeta ya phenyl yasimbuwe n’itsinda rya aside carboxylic (-COOH) ku mwanya wa para. Iki gikora cyane mu guhuza ibinyabuzima, cyane cyane mu mikorere ya Suzuki-Miyaura kugira ngo habeho imigozi ya karuboni na karuboni. Byongeye kandi, ubushobozi bwayo bwo gufatana na diols n’isukari byatumye ikoreshwa mu guteza imbere ibikoresho byo kugenzura isukari no mu buvuzi mu gushushanya enzyme inhibitors na receptor ligands.
