D-SERINE CAS: 312-84-5

D-serine yibanzweho cyane kubera uburyo ishobora gukoreshwa mu kuvura, cyane cyane mu bijyanye n'indwara z'imitsi n'indwara zo mu mutwe. Ubushakashatsi bwerekana ko kongera cyangwa guhindura urugero rwa D-serine bishobora kugira ingaruka ku ndwara nka schizophrenia, indwara ya Alzheimer, no kwiheba. Uruhare rwayo mu guhindura imikorere ya NMDA receptor ruyishyira mu mwanya wayo mu guteza imbere imiti igamije gukemura ibibazo byo mu mutwe, indwara z'amarangamutima, n'indwara z'ubwonko. Byongeye kandi, uruhare rwa D-serine mu gukora synaptic plasticity no mu nzira z'itumanaho ry'imitsi bishimangira akamaro kayo mu kwiga imikorere y'ubwonko no guteza imbere ubuvuzi bw'indwara z'imitsi. Ubushobozi bwayo bwo kongera imikorere ya NMDA receptor no guteza imbere neuroplasticity itanga uburyo bwo gufata ingamba zigamije indwara zijyanye no gucika intege kw'ubwonko, imvune zo mu bwonko, n'izindi ndwara z'ubwonko zitera indwara. Byongeye kandi, uburyo D-serine ikorana na sisitemu za neurotransmitters hamwe n'ingaruka zayo ku gushyuha kw'imitsi byatumye habaho iperereza ku ngaruka zayo ku guhindura ububabare no kurinda ubwonko, bigaragaza ko ishobora gukoreshwa mu gucunga ububabare no kurinda ubwonko ku ndwara zijyanye no kwangirika cyangwa kudakora neza kw'imitsi. Byongeye kandi, D-serine ifite icyizere mu rwego rw'ubuvuzi bwo kuvugurura no gukora imashini, aho ingaruka zayo ku mikurire y'imitsi no gukura kw'imitsi bishobora gutanga uburyo bwo gusana imitsi no guteza imbere uburyo bwo kuvura imvune zo mu bwonko n'indwara zo kwangirika kw'imitsi. Muri make, uruhare runini rwa D-serine mu mikorere y'imitsi, imikorere ya synaptic, n'ubuzima bw'ubwonko ruyishyira nk'ikintu cy'ingenzi mu nzego zitandukanye z'ubushakashatsi n'ikoreshwa mu buvuzi, bitanga uburyo bushoboka bwo kuvura hibandwa ku ndwara z'imitsi n'izo mu mutwe, ndetse no kugira uruhare mu iterambere ry'uburyo dusobanukirwa imikorere y'ubwonko n'indwara z'imitsi.