Cytochalasin B CAS:14930-96-2 Igiciro cy'umukozi

Cytochalasin B ni ikintu karemano gikomoka ku moko atandukanye y'ibihumyo. Ni mu bwoko bw'ibintu bizwi nka cytochalasin, bizwiho kwangiza urusobe rw'uturemangingo.

Ingaruka nyamukuru za cytochalasine B ni ukubuza actin polymerization. Actin ni poroteyine igira uruhare runini mu kubungabunga imiterere n'ingendo z'uturemangingo. Mu kwivanga na actin, cytochalasine B ibangamira imikorere itandukanye y'uturemangingo.

Imwe mu mikoreshereze y'ingenzi ya cytochalasin B ni mu bushakashatsi ku binyabuzima by'uturemangingo. Ikunze gukoreshwa nk'igikoresho cyo kwiga imikorere ya actin n'uruhare rwayo mu mikorere itandukanye y'uturemangingo, nko kwigabanyamo uturemangingo, kugenda kw'uturemangingo, no gukuramo kwa endocytosis. Mu gukumira polimeri ya actin, cytochalasin B yemerera abashakashatsi gukora ubushakashatsi ku mikorere n'akamaro ka actin muri izi nzira.

Byongeye kandi, cytochalasine B yagaragaje ubushobozi bwo kuvura. Yakoreweho ubushakashatsi ku bushobozi bwayo bwo kubuza ubwoko bumwe na bumwe bw'uturemangingo twa kanseri gukura, bigaragaza ko ishobora kuba umuti urwanya kanseri. Byongeye kandi, yagaragaje ubushobozi bwo kurwanya virusi zimwe na zimwe, bigaragaza ko ishobora gukoreshwa mu kuvura virusi.