Concanavalin A CAS:11028-71-0 Igiciro cy'umukozi

Guhuza Uturemangingo: Imwe mu ngaruka zigaragara za Con A ni ubushobozi bwayo bwo gutera guhurirana kw'uturemangingo. Iyi miterere yagize akamaro mu kwiga uburyo uturemangingo dufatana n'uburyo imiterere y'uturemangingo ikorana.

Gutandukanya poroteyine ya Glycoprotein: Con A ihuza by'umwihariko na poroteyine za glyco zirimo mannose ya nyuma n'ibisigazwa bya glucose. Iyi miterere yakoreshejwe mu gutandukanya no gutunganya poroteyine za glycoprotein zivuye mu ruvange rw'ibintu bitandukanye, nk'amazi y'ibinyabuzima cyangwa lysates z'uturemangingo, hakoreshejwe chromatography ya Con A affinity.

Gutahura Glycoproteins: Con A ishobora gukoreshwa mu gupima no gupima glycoproteins mu bipimo. Ukoresheje Con A ihujwe na fluorescent cyangwa enzymes tags, birashoboka kubona cyangwa gupima ingano ya glycoproteins ziri mu gipimo binyuze muri microscopy ya fluorescence cyangwa tekiniki ya enzyme-linked immunosorbent assay (ELISA), uko bikurikirana.

Ibirango by'ubuso bw'uturemangingo: Bitewe n'uko ifitanye isano n'isukari ku buso bw'uturemangingo, Con A ishobora gukoreshwa mu gushyira ibimenyetso ku bwoko runaka bw'uturemangingo cyangwa kwiga imiterere ya glycosylation ku buso bw'uturemangingo. Con A ihujwe na fluorophores cyangwa izindi tagi ituma haboneka ishusho n'isesengura ry'uturemangingo binyuze mu buryo nka flow cytometry cyangwa fluorescence microscopy.

Guhindura ubudahangarwa bw'umubiri: Con A ifite ubushobozi bwo guhindura ubudahangarwa bw'umubiri kandi ishobora kugira ingaruka ku mikorere y'uturemangingo tw'umubiri. Ishobora gushishikariza gukora no kwiyongera kwa lymphocytes T, bigatuma habaho cytokines n'izindi ngaruka z'umubiri. Iyi ngaruka yasuzumwe mu buvuzi bw'umubiri no guteza imbere urukingo, aho Con A yakoreshejwe mu kongera ubushobozi bw'umubiri bwo guhangana n'ubudahangarwa bw'umubiri cyangwa guhindura ubushobozi bw'umubiri bwo kwihanganira ubudahangarwa bw'umubiri.

Igikoresho cy'ubushakashatsi: Con A ni igikoresho gikoreshwa cyane mu nzego zitandukanye z'ubushakashatsi ku binyabuzima. Cyakoreshejwe mu kwiga imikoranire ya karubohidrati na poroteyine, gufatana kw'uturemangingo, imiterere ya glycosylation, n'uburyo ubudahangarwa bw'umubiri bukora. Ubushobozi bwayo bwo gufatana n'isukari runaka butuma igira akamaro mu kwiga no gukoresha glycoproteins na glycolipide.