Clozapine N-oxide CAS: 34233-69-7 Igiciro cy'umukozi

Clozapine N-oxide ni metabolite ikomoka ku muti urwanya indwara zo mu mutwe wa clozapine. Yakunze kwitabwaho mu bushakashatsi kubera uburyo ishobora gukoreshwa muri optogenetics, uburyo bukoresha urumuri mu kugenzura uturemangingo mu turemangingo tuzima, cyane cyane neurons. Mu bushakashatsi bwa optogenetic, clozapine N-oxide ishobora gukoreshwa mu kugenzura imikorere ya receptors za designer zikoreshwa gusa n'imiti ya designer (DREADDs), ari zo molekile zihinduranya zisubiza clozapine N-oxide. Iyi porogaramu yemerera abashakashatsi gukoresha imiyoboro y'ubwonko no kwiga imikorere yayo. Byongeye kandi, clozapine N-oxide nayo yakozweho ubushakashatsi ku ngaruka zishobora kugira ku kuvura indwara zo mu mutwe n'izo mu bwonko.