Boc-Leu-OSu CAS: 3392-09-4

Boc-Leu-OSu ikoreshwa cyane mu ngamba zo guhuza ibinyabuzima n'uburyo bwo guhindura peptide. Mu gukora peptide, byoroshya uburyo ibisigazwa bya leucine bigenzurwa byinjizwa mu buryo bugenzurwa mu buryo bukurikiranye, bigatuma habaho guhuza amatsinda atandukanye y'imikorere, ibirango, cyangwa molekile mu bikorwa bitandukanye. Uku guhindura ibintu mu buryo bunyuranye kwemerera kurema peptide zifite imikorere myinshi zifite imiterere yihariye, nko kongera ubushobozi bwo guhagarara, ubushobozi bwo gushushanya ibintu, cyangwa ubushobozi bwo gufata amashusho. Mu bushakashatsi bwa poroteyine, Boc-Leu-OSu yemerera gushyira poroteyine na peptide mu buryo bwihariye, bigatanga umusanzu mu gusesengura imiterere, inyigo z'imikoranire, n'igerageza rishingiye kuri spectrometry y'ubwinshi. Gushyira Boc-Leu-OSu mu buryo bugenzurwa mu buryo bugenzurwa mu buryo bunoze no gusesengura imikorere ya poroteyine na peptide, bishyigikira iterambere mu gusobanukirwa sisitemu y'ibinyabuzima n'uburyo indwara zigenda. Byongeye kandi, mu iterambere ry'imiti, Boc-Leu-OSu igira uruhare runini mu guhuza imiti ivura na peptide cyangwa poroteyine, ikora sisitemu yo gutanga imiti yihariye, antibody-drug conjugates, cyangwa inkingo zifite imiterere myiza ya pharmacokinetic kandi zikagabanya ingaruka zitari izo. Muri rusange, ubwizerwe bwa Boc-Leu-OSu mu guhindura peptide no guhuza imiterere y’umubiri bituma iba igikoresho cy’ingenzi mu guteza imbere ubushakashatsi mu kuvumbura imiti, ibinyabuzima by’ibinyabutabire, na proteomics, bitanga amahirwe atandukanye yo guteza imbere uburyo bushya bwo gukoresha imiti.