beta-Nicotinamide adenine dinucleotide trihydrate CAS:53-84-9

Ingufu zitangwa: β-NAD+ ni ingenzi cyane mu guhindura ibiryo ingufu. Ikora nk'inyunganiramirire mu guhumeka kw'uturemangingo, yorohereza ihererekanya rya electron ziva muri metabolites zijya mu ruhererekane rw'ihererekanya rya electron. Uku guhererekanya kwa electron ni ingenzi mu gukora ATP, ari na yo nyunganiramirire y'ingufu z'uturemangingo.

Gusana ADN: β-NAD+ igira uruhare mu gusana ADN. Ikora nk'ishingiro ry'imisemburo nka PARPs (Poly [ADP-ribose] polymerases), ikoresha β-NAD+ mu gusana ADN yangiritse bitewe n'imihangayiko itandukanye y'uturemangingo nko kwangirika kwa ADN guterwa n'imirasire, uburozi, cyangwa stress ya oxidative.

Itumanaho rya Seli: β-NAD+ yagaragaye nk'ikintu cy'ingenzi gitanga amakuru kigira uruhare mu nzira zitandukanye z'uturemangingo. Ishobora gukora nk'intangiriro y'uturemangingo dutandukanye dutanga amakuru, nka ADP-ribose na NAADP, bigenga irekurwa rya kalisiyumu n'ihererekanywa ry'amakuru. Byongeye kandi, imikorere ya β-NAD+ ishobora kugira ingaruka ku mikorere ya gene, gusaza, n'izindi nzira z'umubiri.

Uburyo bwo kuvura: Kongera β-NAD+ no guhindura urugero rwa β-NAD+ birimo gukorwaho ubushakashatsi kugira ngo harebwe uburyo bushobora gukoreshwa mu kuvura. Ubushakashatsi buherutse gukorwa bwerekana ko kongera urugero rwa β-NAD+ bishobora kugira ingaruka nziza ku ndwara ziterwa no gusaza, indwara z’ubwonko, indwara z’imikorere y’umubiri, n’ubuzima bw’umutima n’imitsi. Hari kandi ubushakashatsi bukomeje ku ikoreshwa ry’ibintu bibanziriza β-NAD+, nka nicotinamide riboside na nicotinamide mononucleotide, nk’inyongera zishobora kongera urugero rwa β-NAD+ mu mubiri.