Arecoline hydrobromide CAS: 300-08-3

Ingaruka za Arecoline hydrobromide mu buvuzi zirimo gukangura uturemangingo tw’imitsi dukoresha parasympathetic no kongera uburyo bwo kohereza mu bwonko bwa cholinergic. Nubwo mu mateka yakoreshejwe mu buvuzi gakondo kubera ingaruka zayo zo gukangura, ikunze gukorwaho ubushakashatsi ku ruhare rwayo mu bushakashatsi bw’imitsi bujyanye n’uduce twa acetylcholine receptors n’inzira z’imitsi. Mu bushakashatsi bw’ubuvuzi, arecoline hydrobromide ikoreshwa nk'igikoresho cy’ubushakashatsi mu kwiga imikorere ya acetylcholine receptor, gushyuha kw’imitsi, n’uburyo bwo kurekura neurotransmitters. Imiterere yayo ya cholinergic ituma igira akamaro mu gusobanura imikoranire ikomeye iri mu buryo bw’imitsi n’intego zishobora guterwa mu kuvura indwara z’imitsi. Nubwo ifite akamaro mu bushakashatsi, ikoreshwa rya arecoline hydrobromide mu buvuzi ni rike bitewe n’ingaruka zishobora guterwa, harimo ibibazo byo mu gifu, diaphoresis, n’ingaruka z’umutima n’umutima. Byongeye kandi, isano ifitanye no guhekenya betel nut no gutera kanseri bitera impungenge ku ngaruka z’umutekano n’ubuzima mu gihe kirekire. Muri rusange, nubwo arecoline hydrobromide igaragaza icyizere mu bushakashatsi mu kwiga imikorere y’imitsi n’inzira za cholinergic, ikoreshwa ryayo mu buvuzi rigengwa n’ibibazo by’umutekano n’ingaruka mbi zishobora guterwa. Iperereza rikomeje ku miterere yayo mu by’imiti rishobora gutanga ubumenyi ku buryo bushya bwo kuvura bwibanda ku mikorere ya kolineriji ariko bisaba gusuzuma neza ingaruka n’inyungu zishobora guterwa no gukoresha imiti.