Amphotericin B – Ingano y'inshinge CAS: 1397-89-3

Gutera Amphotericin B bikoreshwa mu kuvura indwara zikomeye z’ibihumyo nka candidemia, aspergillosis ikwirakwira, meningitis ya cryptococcal, na mucormycosis, cyane cyane ku barwayi bafite ubudahangarwa bw’umubiri cyangwa abafite ubudahangarwa bw’umubiri budakomeye. Bitewe n’imikorere yayo ikomeye yo kurwanya indwara ziterwa n’imiti, gutera amphotericin B bikunze gufatwa nk’uburyo bwa mbere bwo kuvura indwara zikomeye z’ibihumyo. Abahanga mu by’ubuzima batanga amphotericin B mu mitsi, bakurikirana neza abarwayi mu gihe cyo gutera kugira ngo barebe ingaruka mbi zishobora kubaho, harimo umuriro, ubukonje, n’ingaruka ziterwa no gutera. Igipimo n’igihe cyo gutera amphotericin B bikoreshwa hakurikijwe indwara runaka y’ibihumyo, imiterere y’umurwayi, n’imikorere mibi y’ingingo. Bitewe n’uburozi bwayo n’ubushobozi bwayo bwo gutera ibibazo by’amashanyarazi, gukurikirana hafi imikorere y’impyiko n’urugero rwa electrolyte ni ingenzi mu gihe cyo kuvura amphotericin B. Imiterere ya amphotericin B ishobora gukoreshwa mu kugabanya uburozi bw’impyiko n’ingaruka ziterwa no gutera amphotericin B deoxycholate isanzwe. Gukurikirana buri gihe ingaruka mbi, nko kubura impyiko no kugabanuka k'amaraso mu mubiri, hamwe n'ubuvuzi bukwiye, bifasha gucunga umutekano no kwihanganira uburyo bwo kuvura amphotericin B. Abatanga serivisi z'ubuvuzi basuzuma neza ibyiza byo kuvurwa bakurikije ingaruka zishobora kubaho, bakareba ko abarwayi bahabwa imiti irwanya udukoko ikwiye mu gihe bagabanya ingaruka mbi. Mu kwibasira indwara zikomeye z'udukoko, guterwa amphotericin B bigira uruhare runini mu guhangana n'indwara zishobora guteza ubuzima no gutanga uburyo bwo kuvura abarwayi bahura n'indwara zikomeye z'udukoko.