Asetilikolinesterase CAS:9000-81-1

Anticholinesterase ni ubwoko bw'imiti cyangwa imiti ibuza imikorere ya enzyme acetylcholinesterase. Acetylcholinesterase ni yo ituma acetylcholine ikora mu mubiri. Mu gukumira iyi enzyme, anticholinesterase yongera urugero rwa acetylcholine, bigatuma habaho kwiyongera kwa cholinerike mu mitsi yo mu mutwe no mu gice cy'inyuma cy'ubwonko.

Uburyo bw'ingenzi bwo kuvura indwara zo mu mutwe nka Alzheimer na myasthenia gravis ni ukuvura indwara zo mu mutwe nka Alzheimer na myasthenia gravis. Mu ndwara ya Alzheimer, iyi miti igamije kongera uburyo bwo korohereza ubwonko mu mitsi no kugabanya umuvuduko wo mu bwonko. Mu ndwara ya myasthenia gravis, imiti yo mu mutwe ifasha kunoza uburyo bwo korohereza ubwonko mu mitsi no gukomera kw'imitsi.

Izindi nzira zo gukoresha imiti irwanya kolinesterase zirimo gusuzuma no kuvura uburozi bwa kolinesterase, cyane cyane imiti yica udukoko cyangwa imiti igabanya ubukana bw'imitsi. Iyi miti ishobora gutera gukangura cyane imikorere ya muscarinic na nicotinic, bigatera ibimenyetso nko kunanirwa kw'imitsi, gutigita no kubura umwuka wo guhumeka. Imiti irwanya kolinesterase ishobora guhindura izi ngaruka binyuze mu kongera urugero rwa acetylcholine no guhangana n'ibintu bihumanya.

Gutumiza cyangwa Gusaba Igiciro

Ibisobanuro birambuye ku gicuruzwa

Ibirango by'ibicuruzwa

Ishyirwa mu bikorwa n'ingaruka

Ingaruka za anticholinesterase yerekeza ku bushobozi bw'imiti cyangwa imiti imwe n'imwe bwo kubuza imikorere ya enzyme acetylcholinesterase. Acetylcholinesterase ni yo ituma acetylcholine ikora mu mubiri. Mu gukumira iyi enzyme, anticholinesterases yongera urugero rwa acetylcholine, bigatuma imikorere ya cholinerike yiyongera.

Uburyo bw'ibanze bwo gukoresha imiti igabanya ubukana bw'indwara ya kolinesterase ni ukuvura indwara ziterwa no kugabanuka k'imikorere y'imitsi. Harimo indwara z'imitsi nka Alzheimer na myasthenia gravis. Mu ndwara ya Alzheimer, imiti igabanya ubukana bw'indwara nka donepezil, rivastigmine, na galantamine ikoreshwa mu kubuza acetylcholine gusenyuka no kongera uburyo bwo kolinesterase ikwirakwira mu mitsi. Ibi bishobora gufasha kunoza imikorere y'ubwonko no kugabanya umuvuduko w'indwara.

Mu ndwara ya myasthenia gravis, imiti irwanya kolinesterase nka neostigmine na pyridostigmine ikoreshwa mu kongera uburyo bwo korohereza imitsi. Iyi miti ibuza kolinesterase kandi ikongera urugero rwa acetylcholine mu ihuriro ry’imitsi, ikongera imbaraga z’imitsi kandi ikagabanya intege nke z’imitsi.

Anticholinesterases nazo zifite akamaro ko gusuzuma no kuvura mu gihe cy’uburozi bwa anticholinergerike. Ibinyabutabire bya anticholinergerike, nk’imiti yica udukoko cyangwa imiti igabanya ubukana bw’imitsi, bishobora gutera kuziba cyane kwa cholinergerike bigatera ibimenyetso nko kwitiranya, umutima utera vuba, umunwa wumye, no kutabona neza. Muri ibyo bihe, anticholinesterases nka pralidoxime zishobora gukoreshwa mu gusubiza inyuma ingaruka binyuze mu kongera urugero rwa acetylcholine no guhangana n’ibintu by’uburozi.

Gupakira ibicuruzwa:

Amakuru y'inyongera:

Imiterere	NA
Isuzuma	99%
Isura	Ifu y'umuhondo woroshye
Nimero ya CAS	9000-81-1
Gupakira	Bito kandi byinshi
Igihe cyo Kubika	Imyaka 2
Ububiko	Bika ahantu hakonje kandi humutse
Icyemezo	ISO.