AC-D-Trp-OH CAS: 2280-01-5.

AC-D-Trp-OH ifite akamaro gakomeye muri shimi ya peptide nk'igice cy'ingenzi mu gukora peptide na peptidomimetics. Nk'ikivange cya D-tryptophan cya acetylated, gikora nk'igikoresho cy'ikoranabuhanga cyo kwinjiza ibisigazwa bya chiral byihariye mu minyururu ya peptide binyuze mu buryo bwo gukora peptide y'icyiciro gikomeye n'icyiciro cy'umuti. Abashakashatsi n'abahanga mu bya shimi bakoresha AC-D-Trp-OH kugira ngo bahindure uruhererekane rwa peptide hamwe n'uburyo bwo kugenzura neza imikorere ya peptide, bigatuma hakorwa imiterere mishya ya bioactive na peptides zo kuvura zigamije kwakira, enzymes, cyangwa abatwara mu buryo bw'ibinyabuzima. Byongeye kandi, AC-D-Trp-OH ikoreshwa nk'inkingi y'ubwubatsi bwa chiral mu gukora imiti ihuza imiti, aho stereochemistry yayo yihariye ari ingenzi mu gukora imiti ya chiral n'ibiyigize bihuza bioactive. Chiralité yayo n'ubudahangarwa bwayo bituma iba ingenzi mu gukora imiti, yongera imiterere ya farumasi n'imikorere ya biyolojiya y'imiti ya nyuma. Byongeye kandi, AC-D-Trp-OH ikoreshwa mu bushakashatsi bwa biochemical kugira ngo yige metabolism ya tryptophan, imikorere ya poroteyine, na neurochemistry. Uruhare rwayo mu gusobanura uruhare rw'uturemangingo dukomoka kuri tryptophan mu kohereza imitsi mu bwonko, mu kugenzura amarangamutima, no mu mikorere y'imitsi mu gihe cy'amanywa n'ijoro bigira uruhare mu gusobanukirwa ingaruka zishobora kubaho mu ndwara z'imitsi n'indwara zo mu mutwe. Muri make, AC-D-Trp-OH igira uruhare runini mu guteza imbere ubushakashatsi bwa siyansi, iterambere ry'imiti, n'ubushakashatsi ku binyabutabire, iha abahanga mu bya siyansi n'inzobere igikoresho gikoreshwa mu gusesengura ikoreshwa ry'ibinyabutabire bikomoka kuri tryptophan mu kuvumbura imiti, gukora peptide, no gukora ubushakashatsi ku binyabutabire.