5-Bromouracil CAS: 51-20-7 Igiciro cy'umukozi

5-bromouracil ni ubwoko bwa thymine bukozwe mu buryo bwa sintetike, igice cya ADN. Iyo iboneka muri ADN, 5-bromouracil ishobora guhinduka mu buryo bwa tautomeric, bigatera kwangirika nabi kwa guanine mu gihe cyo kwibasira ADN, bishobora gutera impinduka. Iyi miterere yatumye 5-bromouracil iba ingirakamaro nk'ikintu gihindura impinduka mu ngirabuzimafatizo mu bushakashatsi ku miterere y'uturemangingo, cyane cyane mu kwiga igipimo cy'impinduka mu miterere n'imikorere yabyo. Yanakoreshejwe mu gusuzuma imiterere n'imikorere ya aside nucleic, ndetse no mu bushakashatsi bujyanye no gusana no kwibasira ADN. Byongeye kandi, 5-bromouracil yakoreshejwe mu kwiga impinduka mu ngirabuzimafatizo no kugaragaza imiterere y'uturemangingo mu binyabuzima bitandukanye.