3,6,9,12-tetraazatetradecamethylenediamine CAS:4067-16-7

3,6,9,12-tetraazatetradecamethylenediamine (spermine) ikora nk'ikintu cy'ingenzi mu mikorere itandukanye ya biyoloji. Igira uruhare runini mu mikurire y'uturemangingo, kwiyongera kw'uturemangingo, no gutuza ADN, bigafasha mu mikorere y'ingenzi ya selile. Kuba intanga ngabo iri mu binyabuzima bigaragaza akamaro kayo mu kubungabunga ubusugire bw'uturemangingo no kugenzura imikorere ya fiziki. Byongeye kandi, intanga ngabo ikoreshwa mu bushakashatsi ku binyabuzima bya molekile n'uturemangingo nk'ikintu gikoreshwa mu bushakashatsi ku binyabuzima bya aside nucleic na poroteyine. Ubushobozi bwayo bwo gukorana na ADN, RNA, na poroteyine butuma abashakashatsi bashobora gusesengura uburyo bwa molekile, kugenzura ishyirwa mu bikorwa rya gene, n'imiterere ya chromatin, bikorohereza gusobanukirwa neza imikorere y'ibanze ya biyoloji. Byongeye kandi, intanga ngabo ikoreshwa mu iterambere ry'imiti n'uburyo bwo gutanga imiti bitewe n'imikoranire yayo na aside nucleic n'ingaruka zishobora kubaho mu buvuzi bushingiye kuri gene no ku buvuzi bushingiye kuri aside nucleic. Uruhare rwayo mu guhindura imiterere n'imikorere ya aside nucleic bigaragaza akamaro kayo mu guteza imbere ubuvuzi bushya n'ikoranabuhanga rya biomedical. Byongeye kandi, uruhare rw'intanga ngabo mu ikorwa ry'imiti ihamye hamwe n'imiti imwe n'imwe na biomolecules bigaragaza ubushobozi bwayo nk'urwego rw'imiti ikoreshwa mu gutanga imiti yihariye no kuyivura. Imiterere yayo yihariye iyishyira mu mwanya mwiza mu iterambere ry'imiti mishya n'ikoranabuhanga rya biotechnological. Muri make, 3, 6, 9, 12-tetraazatetradecamethylenediamine (intanga ngabo) igira uruhare runini mu mikorere y'ibinyabuzima, ubushakashatsi ku ngira ngore, no guteza imbere imiti, ikaba ari molekile ifite impande nyinshi ifite ingaruka nyinshi mu bumenyi bw'ubuzima no mu iterambere ry'ubuvuzi.