3- (N-tosyl-L-alaninylazy) -5-fenylpyrrole CAS: 99740-00-8

2 ′ - (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium yumunyu ni imiti yimiti ikoreshwa muburyo bwo gusuzuma no gukora ubushakashatsi.Ni fluorescente yanditseho inkomoko ya acide sialic, ubwoko bwa molekile ya karubone ya hydrata iboneka hejuru ya selile.

Uru ruganda rukoreshwa nka substrate ya enzymes yitwa neuraminidase, ikora kugirango ikureho ibisigazwa bya acide sialic muri glycoproteine na glycolipide.Iyo iyi misemburo ikora kuri 2 ′ - (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium umunyu, irekura ibicuruzwa bya fluorescent bizwi nka 4-methylumbelliferone.

Florescence ikorwa nuruvange irashobora gupimwa no kugereranywa, igatanga amakuru kubikorwa bya enzymes ya neuraminidase.Ibi ni ingirakamaro cyane cyane mukwiga indwara zitandukanye nuburyo bujyanye na aberrant sialic aside metabolism.

Uru ruganda rukoreshwa kandi muburyo bwo gusuzuma, nko mugushakisha kwandura virusi zirimo ibikorwa bya neuraminidase.Muri ubu bushakashatsi, urugimbu rukoreshwa mu kwerekana ko hari virusi yihariye cyangwa gusuzuma imikorere ya neuraminidase inhibitor mu kuvura virusi.

Tegeka cyangwa usabe amagambo

Ibicuruzwa birambuye

Ibicuruzwa

Gushyira mu bikorwa n'ingaruka

Ingaruka: Ingaruka yihariye ya 3- (N-tosyl-L-alaninylazy) -5-fenylpyrrole irashobora guterwa n'imikoranire yayo na sisitemu y'ibinyabuzima.Hatariho amakuru yihariye yerekeye intego cyangwa uburyo bwibikorwa, biragoye kumenya ingaruka zayo.Nyamara, ibikomoka kuri pyrrole byakozweho ubushakashatsi kubikorwa byabo bishobora kurwanya anticancer, anticicrobial, na antifungal.

Gushyira mu bikorwa: Ukurikije imiterere nibikorwa bishobora kuvanga ibintu bisa, ikoreshwa rya 3- (N-tosyl-L-alaninylazy) -5-fenylpyrrole rishobora kugira byinshi bishoboka, harimo:

Ubuvumbuzi bw'ibiyobyabwenge: Uru ruganda rushobora gukoreshwa mu kuvumbura ibiyobyabwenge no mu bikorwa byo kwiteza imbere kugira ngo bige ku ngaruka zishobora kuvura, cyane cyane mu kuvura kanseri, indwara zandura, cyangwa indwara zanduza.
Ubushakashatsi bwibinyabuzima: Abashakashatsi barashobora gukoresha iyi nteruro nkigikoresho cyo gukora iperereza ryimikorere ya selile cyangwa molekile muri laboratoire.Imikoranire yihariye na poroteyine, enzymes, cyangwa izindi biomolecules zirashobora gutanga ubumenyi bwingenzi muburyo bwibinyabuzima.
Synthesis ya chimique: Urusobekerane rushobora kandi gukoreshwa muburyo bwo guhuza ibinyabuzima, bikora nk'inyubako yo kurema molekile nshya hamwe nibikorwa bya biologiya.

Gupakira ibicuruzwa:

Amakuru yinyongera:

Ibigize	C20H20N2O4S
Suzuma	99%
Kugaragara	Ifu yera
URUBANZA No.	99740-00-8
Gupakira	Ntoya kandi nini
Ubuzima bwa Shelf	Imyaka 2
Ububiko	Ubike ahantu hakonje kandi humye
Icyemezo	ISO.