2-Amino-3-(4-hydroxyphenyl) aside propanoic CAS:556-03-6

Ingaruka ku ndwara ya Parkinson: L-DOPA ni wo muti mwiza cyane mu kuvura indwara ya Parkinson. Indwara ya Parkinson iterwa no kubura dopamine mu bice bimwe na bimwe by'ubwonko. L-DOPA ni imbarutso ya dopamine kandi ishobora kwambuka umupaka w'amaraso n'ubwonko kugira ngo yongere urugero rwa dopamine, bityo ikagabanya ibimenyetso by'indwara.

Ikoreshwa mu kuvura indwara ya Parkinson: L-DOPA ikunze gukoreshwa hamwe n'umuti ubuza decarboxylase ku ruhande rw'umubiri (nka carbidopa) kugira ngo wongere imikorere yayo. Umuti ubuza decarboxylase kugabanya ihinduka rya L-DOPA muri dopamine mu ngingo z'umubiri, bigatuma L-DOPA nyinshi zigera mu bwonko.

Kurwanya Ibimenyetso by'Imikorere y'Umuyoboro w'Amaguru: L-DOPA ifasha kugabanya ibimenyetso by'Imikorere y'Amaguru bifitanye isano n'indwara ya Parkinson, harimo guhinda umushyitsi, gukomera, gutinda kw'imigendere, no kudahagarara neza kw'imiterere y'umubiri. Ituma imikorere y'Imikorere y'Amaguru irushaho kuba myiza kandi igatuma abarwayi bongera kugenzura imigendere yabo.

Ingaruka mbi: Nubwo L-DOPA muri rusange igira akamaro mu kuvura ibimenyetso bya Parkinson, ishobora no gutera ingaruka mbi nyinshi. Izi zishobora kuba zirimo dyskinesias (kugenda utabishaka), ibibazo byo mu gifu (nk'isesemi, kuruka, no kuribwa mu nda), umuvuduko muke w'amaraso, kubona ibintu mu buryo butunguranye, no guhinduka kw'ibyiyumvo. Ingaruka mbi zishobora gutandukana mu bukana kandi zigasaba gukurikiranwa witonze no guhindura urugero rw'imiti.

Ubundi buryo bwo gukoresha: Uretse kuvura indwara ya Parkinson, L-DOPA yasuzumwe ku bundi buryo. Yagaragaje ko ishobora mu kuvura indwara y’amaguru adatuza, indwara irangwa no gushaka kwimura amaguru, bigatera kubabara no kugorwa no gusinzira. L-DOPA ishobora kandi kugira ingaruka nziza ku bwoko bumwe na bumwe bwa dystonia, indwara yo mu bwonko.