Candesartan CAS: 139481-59-7 Utanga ibicuruzwa

Candesartan ni antiyotensin II ya reseptor ya I (AT1) antagonist, IC50s = 1.12 na 2.86 nM kuri bovine adrenal cortex hamwe ninkwavu aorta. Guhitamo guhitamo angiotensin II iterwa no kugabanuka kwinkwavu za aortic zidafite inkurikizi ziterwa no kugabanuka guterwa nabandi bakozi nka norepinephrine. , KCl, serotonine, PGF2αor endothelin.

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Candesartan ni AT1 yatoranijwe (angiotensin II reseptor 1) antagonist.Antagonism ya reseptor ya angiotensin ibuza vasoconstriction no gukora aldosterone, bigatuma igabanuka ryamazi hamwe na sodium muri plasma yamaraso.Yerekana ingaruka zirwanya ubukana mubyitegererezo byinyamaswa.Ikoreshwa mukuvura kunanirwa k'umutima, nka antihypertensive.Candesartan ntabwo igira ingaruka ku mibereho ya selile cyangwa ikwirakwizwa ahubwo yongera imvugo ya VEGF na interleukin-8 muburyo bwimico ya selile KU-19-19.Candesartan (0.1 nM) irashobora kugabanya igisubizo ntarengwa cyo kwanduza angiostensin II hafi 50%.

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Amakuru yinyongera:

Ibigize	C24H20N6O3
Suzuma	99%
Kugaragara	Ifu yera
URUBANZA No.	139481-59-7
Gupakira	1KG 25KG
Ubuzima bwa Shelf	Imyaka 2
Ububiko	Ubike ahantu hakonje kandi humye
Icyemezo	ISO.