2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate ni ikinyabutabire gikunze gukoreshwa mu mikorere ya karubohidrati na glycosylation. Ni ikintu gikomoka kuri α-D-galactopyranose, ubwoko bw'isukari, aho amatsinda ya hydroxyl ari ku myanya ya 2, 3, 4, na 6 y'impeta ya galactopyranose aterwa na acetylated. Byongeye kandi, karuboni ya anomeric (C1) y'isukari irinzwe n'itsinda rya trichloroacetimidate, bituma iba electrophile ikomeye mu gihe cy'imikorere ya glycosylation.

Iyi mvange ikunze gukoreshwa nk'ikintu gitera glycosylating kugira ngo ishyiremo galactose moieties mu tunyangingo dutandukanye, nka poroteyine, peptides, cyangwa molecule nto za organic. Ibi bishobora kugerwaho hakoreshejwe uburyo bwo guhuza iyi mvange na nucleophile (urugero, amatsinda ya hydroxyl kuri molecule ishakisha) mu bihe bikwiye. Itsinda rya trichloroacetimidate ryoroshya uburyo galactose moiety ifatana na molecule ishakisha, bigatuma habaho glycosidic bond.

Iyi mvange ikunze gukoreshwa mu gukora glycoconjugates, glycopeptides, na glycolipides. Itanga uburyo bukoreshwa kandi bufite akamaro mu guhindura molekile hamwe n’ibisigazwa bya galactose, bishobora kugira akamaro mu nzego zitandukanye, harimo inyigo z’ibinyabuzima, uburyo bwo gutanga imiti, cyangwa guteza imbere inkingo.

Gutumiza cyangwa Gusaba Igiciro

Ibisobanuro birambuye ku gicuruzwa

Ibirango by'ibicuruzwa

Ishyirwa mu bikorwa n'ingaruka

Glycosylation: Iki gikoresho gihura n'ibintu bitandukanye bya acceptor birimo amatsinda ya hydroxyl, nka alcohols cyangwa amines, kugira ngo bikore imigozi ya glycosidic. Ibi bituma galactose yinjizwa kuri molecule ya acceptor, bigatuma habaho glycoconjugates, glycopeptides, cyangwa glycolipides.

Ubushakashatsi ku binyabuzima n'ibinyabuzima: Iki kinyabutabire gifasha abashakashatsi kwiga imikorere y'ibinyabuzima n'imikoranire y'utunyabutabire dufite galactose. Mu gushyira galactose kuri poroteyine, peptides, cyangwa izindi biomolecules, abashakashatsi bashobora gusuzuma uruhare rwabo mu mikorere y'uturemangingo, imikoranire ya receptor-ligand, n'imikorere y'indwara.

Uburyo bwo gutanga imiti: Iki kinyabutabire gishobora gukoreshwa mu guhindura molecule z'imiti hamwe n'ibisigazwa bya galactose, byorohereza itangwa ry'imiti ku ngingo runaka cyangwa uturemangingo. Galactose ishobora gukora nk'ikinyabutabire cyo kwibandaho, ikamenya uduce twihariye tw’uturemangingo, cyane cyane uturemangingo tw’umwijima. Mu gushyira galactose ku miti, abashakashatsi bashobora kongera ubushobozi bwabo bwo guhitamo no gukora neza mu buvuzi bwabo.

Iterambere ry'urukingo: Molekile zirimo Galactose zigira uruhare runini mu kwitwara kw'ubudahangarwa bw'umubiri, kuko zimenyekana na lectine ziba ku turemangingo tw'ubudahangarwa bw'umubiri. Mu guhuza antigens n'uturemangingo twa galactose hakoreshejwe iki kinyabutabire, abashakashatsi bashobora kongera kwitwara kw'ubudahangarwa bw'umubiri no gukora inkingo nziza kurushaho.

Gutunganya imiti: Iyi mvange ishobora gukoreshwa mu gukora imiti itandukanye aho hakenewe guhindura galactose. Ibi birimo gutegura imiterere y’ibinyabutabire, oligosaccharides, cyangwa glycomimetics, bishobora kongera gukoreshwa mu buvuzi cyangwa nk'ibikoresho by'ubushakashatsi.

Urugero rw'ibicuruzwa

Gupakira ibicuruzwa:

Amakuru y'inyongera:

Imiterere	C16H20Cl3NO10
Isuzuma	99%
Isura	Ifu y'umweru
Nimero ya CAS	86520-63-0
Gupakira	Bito kandi byinshi
Igihe cyo Kubika	Imyaka 2
Ububiko	Bika ahantu hakonje kandi humutse
Icyemezo	ISO.