2 ′ - (4-METHYLUMBELLIFERYL) -ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS: 76204-02-9

2 ′ - (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium yumunyu ni imiti yimiti ikoreshwa muburyo bwo gusuzuma no gukora ubushakashatsi.Ni fluorescente yanditseho inkomoko ya acide sialic, ubwoko bwa molekile ya karubone ya hydrata iboneka hejuru ya selile.

Uru ruganda rukoreshwa nka substrate ya enzymes yitwa neuraminidase, ikora kugirango ikureho ibisigazwa bya acide sialic muri glycoproteine na glycolipide.Iyo iyi misemburo ikora kuri 2 ′ - (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium umunyu, irekura ibicuruzwa bya fluorescent bizwi nka 4-methylumbelliferone.

Florescence ikorwa nuruvange irashobora gupimwa no kugereranywa, igatanga amakuru kubikorwa bya enzymes ya neuraminidase.Ibi ni ingirakamaro cyane cyane mukwiga indwara zitandukanye nuburyo bujyanye na aberrant sialic aside metabolism.

Uru ruganda rukoreshwa kandi muburyo bwo gusuzuma, nko mugushakisha kwandura virusi zirimo ibikorwa bya neuraminidase.Muri ubu bushakashatsi, urugimbu rukoreshwa mu kwerekana ko hari virusi yihariye cyangwa gusuzuma imikorere ya neuraminidase inhibitor mu kuvura virusi.

Tegeka cyangwa usabe amagambo

Ibicuruzwa birambuye

Ibicuruzwa

Gushyira mu bikorwa n'ingaruka

Igikorwa cya Neuraminidase Assay: Uru ruganda rukoreshwa mugupima ibikorwa byimisemburo ya neuraminidase mubyitegererezo byibinyabuzima.Mugukurikirana fluorescence yakozwe, abashakashatsi barashobora kumenya urwego rwibikorwa bya neuraminidase, bishobora gufasha mukwiga indwara zitandukanye.

Kumenya kwandura virusi: Indwara nyinshi za virusi, harimo ibicurane, zirimo ibikorwa bya neuraminidase.Uru ruganda rushobora gukoreshwa mugushakisha no kugereranya ahari virusi yihariye mugupima ibikorwa bya fluorescent.Ni ingirakamaro cyane mugusuzuma imikorere ya neuraminidase inhibitor mu kuvura virusi.

Isesengura rya Glycosylation: Acide Sialic ni igice cyingenzi cya glycoproteine na glycolipide.Mugushyiramo 2 '- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acide sodium yumunyu wa sodium mubushakashatsi, abashakashatsi barashobora kunguka ubumenyi kubijyanye na acide sialic metabolism, uburyo bwa glycosylation, hamwe nibikorwa bifitanye isano na physiologiya.

Kuvumbura ibiyobyabwenge: Neuraminidase inhibitor ni icyiciro cyimiti ikoreshwa mukuvura indwara zanduye.Uru ruganda rushobora gukoreshwa mubushakashatsi bwo kuvumbura ibiyobyabwenge, bifasha abashakashatsi kumenya no gusuzuma ibishobora kubuza ibikorwa bya neuraminidase.

Gupakira ibicuruzwa:

Amakuru yinyongera:

Ibigize	C21H26NNaO11
Suzuma	99%
Kugaragara	Ifu yera
URUBANZA No.	76204-02-9
Gupakira	Ntoya kandi nini
Ubuzima bwa Shelf	Imyaka 2
Ububiko	Ubike ahantu hakonje kandi humye
Icyemezo	ISO.